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Natrium-Zirkonium-Cyclosilikat ist ein Ionenaustauscher zur Behandlung einer Hyperkaliämie. Es wird als Lokelma® unter dem Handelsnamen vertrieben und hat einen Zusatznutzen, der nicht belegt ist.

Lokelma 10 g administered three times daily lowered serum potassium by -0.7 mmol/L at 48 hours (p < 0.001 vs. placebo); statistically significant 14% potassium reduction was observed 1 hour after the first dose. Patients with higher starting。

Lokelma est indiqué dans le traitement de l’hyperkaliémie chez l’adulte (voir rubriques 4.4 et 5.1). Phase de correction La dose initiale recommandée de Lokelma est de 10 g, administrée trois。

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